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Cure Parkinson's

Annual Report and Financial Statements 2024-25

Cure Parkinson's 2024-25 annual report marks the charity's 20th year, covering a transformative period in its research funding. Highlights include a £5.7m commitment to EJS ACT-PD — the UK's first multi-arm multi-stage Parkinson's trial platform — and the opening of recruitment for the ASPro-PD phase 3 ambroxol trial. Nine new projects were funded across clinical, preclinical and observational research, with cumulative research investment now exceeding £25.4m. Reserves grew to £10.8m for the first time, giving the charity the financial agility to lead on larger, more ambitious programmes. The charity aims to raise and invest a further £20m over the next three years.

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About

EJS ACT-PD multi-arm multi-stage clinical trial platform (£5.7m committed, part of £16.1m consortium); ASPro-PD phase 3 ambroxol trial (recruitment opened Feb 2025); SLEIPNIR trial platform (£1.1m committed); DAPA-PD anti-inflammatory phase 2 trial (Cambridge, £1.065m); 9 new projects funded including 3 clinical trials; International Linked Clinical Trials (iLCT) programme; collaboration with Alzheimer's Research UK; policy campaigning via Parky Charter and Neurological Alliance

Key Metrics

Key Metric 1 £8.1m committed to new research projects; 32 active projects worth £18.5m; cumulative research funding exceeds £25.4m since 2005
Key Metric 2 Cure Parkinson's is a UK charity founded in 2005, now in its 20th year, with a singular focus on funding research to slow, stop and reverse Parkinson's. Around 166,000 people in the UK and an estimated 11.8 million globally live with the condition. The charity funds and facilitates research across clinical trials, preclinical studies and drug discovery, working collaboratively with international partners and academic institutions.
Key Metric 3 Disease-Modifying Research; Clinical Trials; Drug Repurposing; International Collaboration; Policy & Advocacy

Key Outcomes

  • £8.1m committed to new research in 2024-25; 32 active projects worth £18.5m across 38 institutions in 11 countries; reserves grew to £10.8m enabling larger-scale commitments
  • 9 new projects funded including 3 clinical trials; ASPro-PD opened recruitment Feb 2025; EJS ACT-PD platform — a global first for Parkinson's — set to begin recruiting participants in second half of 2025
  • 11,102 donations received; cumulative research investment exceeds £25.4m across 80 projects since 2005; new collaboration with Alzheimer's Research UK; Parky Charter handed to Downing Street April 2024

Geography

UK-Wide

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