Closer to a Cure — 15 Years of Impact

Brain Tumour Research was founded in 2009 by families affected by brain tumours, with a mission to increase UK research investment and fund Centres of Excellence. Their 2025 impact report — marking 15 years — documents £46.4m contributed to the national research effort, five active Centres of Excellence, 260 research personnel supported, and major breakthroughs including an FDA-designated blood test for brain tumour detection and HIV drugs repurposed for schwannoma treatment.

Report snapshot
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📋About

Centres of Excellence at University of Plymouth, Imperial College London, Queen Mary University of London, Institute of Cancer Research (paediatric), Scottish Centre (Edinburgh/Glasgow); PRIME patient involvement programme, BTR-NTA therapeutics accelerator, BRAIN UK tissue bank Custom geography from upload: UK

📊Key Metrics

£23.2m awarded to research since 2009; £18.2m directly to Centres of Excellence; Centres leveraged additional £23.2m — total £46.4m contribution to national investment Key Metric 1
5 Centres of Excellence funded across UK; 39 PhD students supported; 260 research personnel supported; 167 publications underpinned Key Metric 2
130+ research projects supported through Funded Initiatives; 23 novel therapies reviewed by BTR-NTA; BRAIN UK tissue bank holds 210,000+ cases and has supplied 26,000+ samples to 110+ studies Key Metric 3

Key Outcomes

  • Blood test for high-grade brain tumours granted FDA Breakthrough Device Designation (2023); Barts Brain Tumour Centre grew from zero clinical trials in 2019 to running the most brain tumour clinical trials of any UK neuro-oncology centre in 2024
  • Scottish Brain Tumour Research Centre launched January 2025 with £2.4m over five years; PRIME patient involvement initiative helped secure over £28m in brain tumour trial funding
  • National annual spend on brain tumours increased from under £4m in 2009 to over £17m; 140 global research group collaborations across 19 countries; HIV anti-retroviral RETREAT trial launched June 2024 for schwannoma/NF2 patients

📍Geography

UK-Wide

2026 Enhanced

Impact — Winter 2026

Total income £18,180,000 and total expenditure £18,560,000 (year ended 31 December 2024, charity no. 1084958 England/Wales and SC039654 Scotland); in 2024 spent £3.8m on charitable activities including £1,079,000 on research, £1,366,000 on EB Community Support, £943,000 on public education, £270,000 on EB healthcare and £185,000 on respite breaks
Key Metric 1
700+ members supported through in-person visits and support calls in 2025; 697 support grants allocated in 2025 for essential items including specialist clothing, cooling fans and sheepskin liners; 2 new holiday homes purchased in 2025 with over 700 guests enjoying holiday homes; £34,000 raised through 2025 winter 'The Longest Night' appeal
Key Metric 2
Largest global investment in EB research to date: multi-million-pound drug repurposing trial provisionally agreed with LifeArc partner at Guy's and St Thomas' NHS Foundation Trust and King's College London; EB Priorities Setting Partnership study completed mapping global research priorities for all four main EB forms
Key Metric 3
£34,000 raised in 2025 winter appeal supporting families like Darcie's with specialist items, emotional support and research; 697 support grants delivered in 2025; first Members Connect event in Northern Ireland; EB Priorities Setting Partnership study completed providing global research roadmap
2025 Enhanced

Impact Report 2025

22,507 households helped through RBL casework and specialist support services across 66 countries
Key Metric 1
22,600 grants given to those in need, totalling £11.8 million
Key Metric 2
733 beneficiaries represented at tribunals, resulting in £24.5 million in War Pensions awards
Key Metric 3
1,548 new families living with dementia supported by RBL Admiral Nurses service
2025 Enhanced

Our Impact 2024-25

3,600 blind veterans received support across the UK; 447 new blind veterans started receiving support in 2024/25
Key Metric 1
1,598 referrals to rehabilitation services completed; 313 veterans received assistive technology training
Key Metric 2
997 volunteers donated 26,824 hours of support; befriending service awarded Quality in Befriending Excellence — one of only 11 organisations in the UK to achieve this
Key Metric 3
1,831 National Creative Wellbeing Project packs issued to help veterans reconnect with creativity and independence